Mike Garofolo reports that San Francisco 49ers quarterback Brock Purdy will return as early as Week 11 from his toe injury.

An incident involving San Francisco 49ers star running back Christian McCaffrey led to a punishment from the NFL this weekend.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 10 on a sizzling 47-29 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

Asante Samuel Jr. to boost secondary after injuries. Analyst explains urgency, fit, and postseason Super Bowl impact.

Brady is referencing the 49ers drafting quarterback Giovanni Carmazzi over him in the 2000 NFL Draft. He was selected in the third round, at pick 65, by the 49ers. He played just two seasons in San Francisco before leaving the NFL less than two years after being drafted.

The San Francisco 49ers on Saturday elevated rookie DT Sebastian Valdez and D-lineman Clelin Ferrell to face the Los Angeles Rams on Sunday.

San Francisco 49ers head coach Kyle Shanahan announced the team's starting quarterback for Week 10's matchup against the Rams.