Histopathological findings of the tongue lesion. (A) Squamous mucosa showing hyperplastic psoriasiform epithelium (Hematoxylin & eosin, ×100). (B) Munro’s microabscess (arrow; Hematoxylin & eosin, ...

SCC is a common skin cancer, more aggressive than basal cell carcinoma, with potential to metastasize. Long-term UV exposure is a primary cause, with SCC often appearing on sun-exposed areas.

In a retrospective study, Hispanic patients developed a second cutaneous squamous cell carcinoma (cSCC) less frequently and later than non-Hispanic patients. Researchers evaluated 65 Hispanic patients ...

Squamous cell carcinoma of the bladder is rare, accounting for 2% to 5% of bladder cancers in the U.S., and is linked to chronic bladder irritation. Diagnosis involves cystoscopy, biopsy, and imaging ...

Double primary malignant tumors are infrequently encountered, with esophageal squamous cell carcinoma (ESCC) co-occurring with malignancies in other organs, representing a rare clinical entity. The ...

Early-stage squamous cell carcinoma of the esophagus is primarily treated with endoscopic resection, while esophagectomy or chemoradiotherapy may be considered for select patients based on staging and ...

Cutaneous squamous-cell carcinoma (SCC) is primarily caused by oncogenesis mediated by ultraviolet radiation, and β-human papillomavirus (β-HPV) is believed to be a mere facilitator that is ...

A team led by researchers at Baylor College of Medicine and Washington University School of Medicine has shed light on the process that drives Barrett’s esophagus formation. This condition affects the ...

Tissue epithelia maintain their lineage identity under normal conditions but occasionally undergo ‘reprogramming’ into another lineage—a phenomenon known as metaplasia. Notable examples include ...

Shlomo Koyfman, MD, discusses the MK-3475-630/ KEYNOTE-630 trial, which focused on patients with high-risk cutaneous squamous cell cancer. Shlomo Koyfman, MD, a radiation oncologist at Cleveland ...

(a) Diagnosed with achalasia; (b) Underwent peroral endoscopic myotomy (POEM) surgery for achalasia; (c) Severe reflux symptoms 23 months later; (d) Esophageal squamous cell carcinoma located 25 cm ...