Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system—a group of proteins that ...

Long-term (chronic) inflammation in your body has been linked with several types of cancer, in addition to other serious conditions. One recent study found that 20% of cancer-related deaths were ...

Exercise reshapes inflammation at the cellular level, and understanding exactly how could unlock therapies for chronic disease and age-related frailty. At the Langston Lab at Yale School of Medicine, ...

A new Aging Cell study reveals that the inflammatory cytokine TNF-α drives muscle wasting in COPD by activating a p53-Prodh2-mitochondrial ROS cascade that leaks mitochondrial DNA and triggers ...

It is estimated that more than 5 million people worldwide suffer from ulcerative colitis, a chronic inflammation of the colon that often progresses in stages whose causes have not yet been fully ...

Chronic inflammatory bowel disease is challenging to treat and carries a risk of complications, including the development of bowel cancer. Young people are particularly affected: when genetic ...

Periodontal disease, commonly known as periodontitis, is a chronic inflammatory condition initiated by bacterial biofilms on the tooth surface and gingival margin. While the primary manifestation is ...

When people think of depression, they often think of 'stress', 'neurotransmitters in the brain', or 'environment and ...

Chronic inflammation has been one of the most heavily researched topics in the health world in recent years, with doctors continuing to uncover all the ways it can be harmful to your health.

There are two types of inflammation: acute and chronic. Acute inflammation is the kind that lasts a few hours, days, or weeks, and it’s helpful to healing. It’s your immune system’s response when ...