Setting NFL records is cool - but winning is much cooler in the eyes of Arizona Cardinals QB Jacoby Brissett. In the process of being routed by the San Francisco 49ers in Week 11, Brissett set an NFL record with 47 pass completions today. Brissett, when speaking with reporters after the loss, says he couldn't care less.

Expert recap and game analysis of the San Francisco 49ers vs. Arizona Cardinals NFL game from November 16, 2025 on ESPN.

Daryl Johnston and Kevin Kugler broke down the San Francisco 49ers massive win over the Arizona Cardinals in Brock Purdy's return.

An injured Kyler Murray, a depleted backfield and really, inconsistent football. It didn’t stop today either in their loss to the San Francisco 49ers in Week 11. Let’s take a look at some key stats that led to the Cardinals' seventh loss of the season:

There is no sugarcoating it, the Arizona Cardinals are in a total free fall. The early stages of this brutal skid were defined by heartbreaking losses, like blown fourth-quarter leads to the Tennessee Titans and the San Francisco 49ers.

Brock Purdy found George Kittle for 4-yard TD, extending the San Francisco 49ers lead over the Arizona Cardinals.

Arizona Cardinals safety Budda Baker has been fined by the NFL following Week 11 action. Here’s what led to the league’s decision