The San Francisco 49ers defeated the Arizona Cardinals 41-22 on Sunday at State Farm Stadium, and head coach Kyle Shanahan spoke after the win.

The San Francisco 49ers and Carolina Panthers are in a race for a playoff spot, but the 49ers are favored big in their Week 12 showdown on MNF.

The Eagles look good enough to repeat, at least on one side of the ball; the Broncos remain red hot after taking down the ...

The "49ers Postgame Live" crew highlights running back Christian McCaffrey after San Francisco's 41-22 win over the Arizona ...

The San Francisco 49ers finished their Week 11 contest with a 41-22 win over the Arizona Cardinals at State Farm Stadium.

Highlights from the Week 11 matchup between the San Francisco 49ers and the Arizona Cardinals during the 2025 NFL season.

In a battle of 7-2 teams, it was the Rams who survived a heavyweight showdown in the NFC West. The Seahawks have no one to ...

The San Francisco 49ers had huge plays on both sides of the ball to earn a blowout win over the Arizona Cardinals. Here are ...

Seattle kicker Jason Myers misses a 61-yard field goal as time expires as the Rams escape with a 21-19 win for their fifth ...

In the afternoon round of four matchups, the Los Angeles Rams defeated the Seattle Seahawks to gain sole possession of first ...

San Francisco 49ers quarterback Brock Purdy returns to action and his first completion goes for a 25-yard gain to wide ...

Brock Purdy hit George Kittle for 30-yard TD, extending the San Francisco 49ers lead over the Arizona Cardinals.