BACKGROUND: Fontan circulatory failure (FCF) is a chronic state in palliated single ventricle heart disease with high morbidity and mortality rates, including heart failure, multisystem end-organ ...

BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

BACKGROUND: Evaluation of whether dyspnea has a cardiac cause is essential. Guidelines from 2016 were reported to result in a ...

European Stroke Organisation Conference May 21–23, 2025 Session: Intravenous Thrombolysis in Acute Ischemic Stroke: Expanding Indications and Evidence Gaspard Gerschenfeld from Paris, France, ...

Cardiovascular-kidney-metabolic (CKM) syndrome is a novel construct recently defined by the American Heart Association in response to the high prevalence of metabolic and kidney disease.

Herein we report results of the 1-year, double-blind, placebo-controlled part of the phase 3 study ORION-13 (Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial ...

In this American Heart Association scientific statement, we aim (1) to explore the definitions and conceptual framework of palliative care, (2) to review data supporting its use in noncardiac and ...

Blockade of IL1RAP (interleukin 1 receptor associated protein) was recently shown to reduce atherosclerosis in mice, but the effect on human vascular cells is largely unknown. Targeting the IL1RAP ...

Chronic coronary disease (CCD) is the leading cause of death in the United States. There is an ongoing imperative to disseminate evidence-based and patient-centered care recommendations that further ...

Since then, additional evidence associating and causally linking sleep to CMH has accumulated. As a result, in 2022, the American Heart Association added sleep duration as an eighth metric of CMH, ...

Cardiac rehabilitation (CR) reduces mortality rates and improves the quality of life of patients with cardiovascular disease (CVD), 1 and its use is supported by American College of ...

Historically, investments in specialized pediatric care, such as congenital cardiac care, have been deprioritized in LMIC due to the greater burden of “high prevalence” conditions such as malnutrition ...