Its speech measures reflected clinical scores and HD-related changes over time, suggesting it could be used as a remote ...
September brought progress across the HD research landscape. From brain waves and visual thinking to DNA repeats, nutrition, ...
Huntington’s disease (HD) is typically viewed as a brain disorder, but new research highlights its lesser-known effects on the body, especially on muscles, fat, and nutrition, even in the early stages ...
Day 1 of HD2026 is a wrap! From what human brains can teach us about HD, to HTT1a, somatic CAG expansion and the normal biology of HTT, today’s talks spanned the spectrum from fundamental biology to ...
PROTACs act like a precision pruning tool, trimming away toxic huntingtin protein while leaving the healthy form intact. In cells and HD mice, this targeted clean-up improved health and slowed disease ...
From the clinic, we heard from uniQure about their recent FDA meeting, a stem cell trial dosed its first participant, and Skyhawk shared data on SKY-0515. In the lab, the science of slowing HD at the ...
A new study suggests that reduced awareness of symptoms, known as anosognosia, may appear even in the earliest stages of HD. The findings highlight that understanding symptom progression requires more ...
One of the biggest challenges in clinical research is making the most of the information that trials generate. A solution to this is to share data between stakeholders so that everyone can learn from ...
New 12-month data from Skyhawk’s SKY-0515 is in and all four measures that make up the cUHDRS are at or above baseline, beating expected natural decline. Plus, a first look at expanding US trial sites ...
Four years after a single treatment, the high-dose AMT-130 group continues to show encouraging signs of slower HD progression ...
A review of 23 studies found that EEG changes were linked to disease progression and clinical measures in HD. While more research is needed, EEG holds potential to become a simple, non-invasive ...
On December 3, 2024 a study site gave word that the very first person received a new drug, called ALN-HTT02, as part of a ...
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