In this review, we provide a state of the art of liver transplantation in children, as the procedure is now carried out for more than 30 years and most of our paediatric colleagues are managing these ...

Objectives Multiplex gastrointestinal PCR (GI-PCR) allows fast and simultaneous detection of 22 enteric pathogens (including Campylobacter, Salmonella , Shigella /enteroinvasive Escherichia coli (EIEC ...

Our aim was to develop guidance for general paediatricians and primary care physicians in diagnosing and managing cow’s milk protein allergy in infants. The guidelines were developed by discussion ...

Childhood encephalopathy is an uncommon but significant paediatric presentation and is associated with significant mortality and long-term morbidity in survivors. By definition it is a somewhat ...

Objective Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency is an inherited adrenal steroid synthesis ...

Charts are presented which give centile standards for boys' and girls' heights at ages 2 to 9 when parents' height is allowed for. Mid-parent height is used (i.e. the average of father's and mother's ...

Background Most guidelines recommend the use of capillary refill time (CRT) as part of the routine assessment of unwell children, but there is little consensus on the optimum method of measurement and ...

Background We sought to measure the diagnostic accuracy of D-dimer in children with suspected pulmonary embolism (PE). Methods We queried our electronic medical record for quantitative D-dimer values ...

Background National and international guidelines recommend that psychosocial support should be a key component of the care offered to children and adolescents experiencing gender ...

### Key practice points Childhood cancer treatment often impairs reproductive function and future fertility. Management requires assessment of fertility risk and consideration of fertility ...

This series of systematic reviews1–4 was commissioned by WHO in July 2022 to inform their guideline review process (www.who.int). The aim was to identify the current evidence for developing WHO ...

Attention deficit hyperactivity disorder (ADHD) affects around 1–3% of children. There is a high level of comorbidity with developmental and learning problems as well as with a variety of psychiatric ...