Injuries always have a significant effect on the NFL season, but some teams are bearing the brunt of absences more than ...

The injured 49ers are in real trouble, the Eagles look like (hopeful!) pretenders, and more in our weekly NFL power rankings.

One anonymous NFL executive thinks the San Francisco 49ers should look into trading Brock Purdy to go with a "cheaper" ...

San Francisco 49ers rookie Ricky Pearsall made his NFL debut on Sunday, Oct. 20, two months after he was shot in the chest ...

San Francisco 49ers wide receiver Brandon Aiyuk suffered a torn ACL Sunday against the Chiefs. Here, I look at five options ...

Deebo Samuel is in a hospital dealing with pneumonia, meaning the San Francisco 49ers have health concerns with their top two ...

NFL Week 8 odds, picks, predictions, TV and streaming information for Sunday Night Football game between Dallas Cowboys and ...

San Francisco 49ers wide receiver Ricky Pearsall will be activated for the team’s Week 7 matchup against the Kansas City ...

Week 7 could represent the best game played at Levi's Stadium this season as the Kansas City Chiefs are coming to town.

NFL Week 7 odds, picks, predictions, TV and streaming information for the Sunday football game between the Kansas City Chiefs ...

The Super Bowl rematch is here. The Kansas City Chiefs (5-0) head to California to face the San Francisco 49ers (3-3) in a ...

Looking at Sunday’s Dallas Cowboys at San Francisco 49ers Week 8 NFL odds, lines and trends. Here’s what you need to know.