Injuries always have a significant effect on the NFL season, but some teams are bearing the brunt of absences more than ...

As long as Kyle Shanahan is their coach and they're packed with superstars like Fred Warner, Nick Bosa, and George Kittle, ...

One anonymous NFL executive thinks the San Francisco 49ers should look into trading Brock Purdy to go with a "cheaper" ...

San Francisco 49ers rookie Ricky Pearsall made his NFL debut on Sunday, Oct. 20, two months after he was shot in the chest ...

San Francisco 49ers wide receiver Brandon Aiyuk suffered a torn ACL Sunday against the Chiefs. Here, I look at five options ...

Deebo Samuel is in a hospital dealing with pneumonia, meaning the San Francisco 49ers have health concerns with their top two ...

NFL Week 8 odds, picks, predictions, TV and streaming information for Sunday Night Football game between Dallas Cowboys and ...

San Francisco 49ers wide receiver Ricky Pearsall will be activated for the team’s Week 7 matchup against the Kansas City ...

The last time star wide receiver Brandon Aiyuk and the San Francisco 49ers took on the Kansas City Chiefs, it did not go ...

The Kansas City Chiefs continued a run of dominance over the San Francisco 49ers — while also keeping the NFL’s only unbeaten ...

Week 7 could represent the best game played at Levi's Stadium this season as the Kansas City Chiefs are coming to town.

Kansas City Chiefs quarterback Patrick Mahomes (15) looks for an open receiver past the defense of the San Francisco 49ers in ...