Injuries always have a significant effect on the NFL season, but some teams are bearing the brunt of absences more than ...

The injured 49ers are in real trouble, the Eagles look like (hopeful!) pretenders, and more in our weekly NFL power rankings.

One anonymous NFL executive thinks the San Francisco 49ers should look into trading Brock Purdy to go with a "cheaper" ...

San Francisco 49ers rookie Ricky Pearsall made his NFL debut on Sunday, Oct. 20, two months after he was shot in the chest ...

San Francisco 49ers wide receiver Brandon Aiyuk suffered a torn ACL Sunday against the Chiefs. Here, I look at five options ...

The Kansas City Chiefs are looking to stay undefeated as they face the San Francisco 49ers in a Super Bowl streak.

Brock Purdy's struggles during a Super Bowl LVIII rematch with the Kansas City Chiefs on Sunday could force the San Francisco ...

Deebo Samuel is in a hospital dealing with pneumonia, meaning the San Francisco 49ers have health concerns with their top two ...

Micah Parsons isn't sure if the first injury absence of his career will end for the Dallas Cowboys against rival San ...

How does every NFL team stack up against each other going into Week 8 with a lot of teams making statement victories in Week ...

Jauan Jennings, wide receiver for the San Francisco 49ers, suffered a significant injury during a game against the Seattle ...

The strength of the San Francisco 49ers’ offense the past few seasons has been the number of dynamic playmakers that makes it ...