Karen Read on Tuesday disputed Norfolk Superior Court Judge Beverly Cannone’s claim that jurors in her murder retrial are “fed up” with the case.

For the second time in a week, Judge Beverly Cannone denied Karen Read's attorneys' request for a mistrial after they accused the prosecution of misconduct.

A conviction of any kind would almost certainly prompt a series of appeals by Karen Read. Here are the possible outcomes and what would happen next.

With no verdict in sight just yet, Judge Beverly Cannone dismissed jurors in Karen Read’s retrial for the weekend at 4:30 p.m. Deliberations will resume Monday at 9 a.m., she said, reminding the jury to avoid independent research and be cautious of their social media use.

Karen Read proposed that she personally select which of the jurors would serve as alternates in her murder trial — an idea the judge denied.

Read, 45, is charged with second-degree murder in the death of O’Keefe, who was found outside the home of a fellow Boston police officer on Jan. 29, 2022. Norfolk County prosecutors say Read struck O’Keefe with her SUV while driving intoxicated. Read’s attorneys say her car never struck O’Keefe and that others are to blame for his death.