Brock Purdy returned from a six-game absence to throw three touchdowns as the 49ers (7-4) romped to a 41-22 win over the host ...

So much went right — and some went wrong — as the 49ers walloped the host Arizona Cardinals 41-22 in Brock Purdy’s comeback.

In the other battle of NFC West foes, the 49ers blew out the Arizona Cardinals on the road in Brock Purdy's return to sweep ...

The San Francisco 49ers had huge plays on both sides of the ball to earn a blowout win over the Arizona Cardinals. Here are ...

The San Francisco 49ers blew out the Arizona Cardinals, but there was a lot happening in the Week 11 matchup. Here are the ...

» Not only did the Niners’ tight end catch a touchdown of his own, but he was instrumental on the 49ers’ third touchdown of ...

For the first time since Week 1, the San Francisco 49ers had all of their starters back. Sure enough, it equates to their ...

An injured Kyler Murray, a depleted backfield and really, inconsistent football. It didn’t stop today either in their loss to ...

Jacoby Brissett completed an NFL-record 47 passes, but San Francisco's offense rolled in Purdy's first game in weeks.

On the 49ers' first touchdown of the game, linebacker Akeem Davis-Gaither was matched up with star tight end George Kittle in ...

The San Francisco 49ers open the game with a 98-yard kick return and running back Christian McCaffrey caps off the drive on ...

The San Francisco 49ers are dealing with multiple new injuries after Sunday's win in Arizona, including one to their kicker.