Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system—a group of proteins that ...

A new Aging Cell study reveals that the inflammatory cytokine TNF-α drives muscle wasting in COPD by activating a p53-Prodh2-mitochondrial ROS cascade that leaks mitochondrial DNA and triggers ...

Exercise reshapes inflammation at the cellular level, and understanding exactly how could unlock therapies for chronic disease and age-related frailty. At the Langston Lab at Yale School of Medicine, ...

When people think of depression, they often think of 'stress', 'neurotransmitters in the brain', or 'environment and ...

Cortisol, the primary glucocorticoid hormone, plays a central role in the body's stress response and immune regulation. Released by the adrenal cortex via the hypothalamic-pituitary-adrenal (HPA) axis ...

Five years after the start of the pandemic, a group of researchers from Beth Israel Deaconess Medical Center is one step closer to identifying the cause of the mysterious and debilitating chronic ...

There are two types of inflammation: acute and chronic. Acute inflammation is the kind that lasts a few hours, days, or weeks, and it’s helpful to healing. It’s your immune system’s response when ...

Chronic inflammation has been one of the most heavily researched topics in the health world in recent years, with doctors continuing to uncover all the ways it can be harmful to your health.