After another inept defensive performance and a hallow offensive output, the Arizona Cardinals sit at 3-7 and now host the Jacksonville Jaguars on Sunday. The Jaguars only open as small favorites, so things are not completely off the rails yet.

The 49ers' team captains stepped up in Arizona. One of them, George Kittle, said the team is positioned right where it needs to be.

Brock Purdy returned from a six-game absence to throw three touchdowns as the 49ers (7-4) romped to a 41-22 win over the host Cardinals (3-7).

With the activation of linebacker BJ Ojulari from PUP Saturday and the addition of linebacker Mack Wilson Sr. to IR, the Cardinals now have 13 players placed on IR since the cut to 53, three on IR prior to the cut to 53 and one, cornerback Sean Murphy-Bunting, on reserve/non-football injury, also done prior to the reduction to 53.

With the defense and special teams coming up with big plays, the 49ers dominate Cardinals in Brock Purdy’s return.

Setting NFL records is cool - but winning is much cooler in the eyes of Arizona Cardinals QB Jacoby Brissett. In the process of being routed by the San Francisco 49ers in Week 11, Brissett set an NFL record with 47 pass completions today. Brissett, when speaking with reporters after the loss, says he couldn't care less.

The Cardinals have now lost seven of their last eight, including two straight blowouts to divisional opponents.

Kris Boyd, who played with the Cardinals in 2023 and is currently with the New York Jets, was shot early Nov 16 in Midtown Manhattan, police said.