THP reports that Interstate 65 North at Mile Marker 33.2 is closed for an extended period of time for a serious injury crash.

Lake County license plate readers detected the car involved in an Amber Alert for a missing 8-year-old boy near I-65 and U.S.

The crash was reported at 6:30 p.m. and a TDOT spokesperson said the site would not be totally cleared until 10 p.m.

INDIANAPOLIS — Authorities are investigating after a person was killed in an overnight crash on Interstate 65 northwest of ...

Two people were injured after a terrifying crash on Interstate 65 in central Kentucky early Thursday morning. Two semis slide off the interstate and crashed into a house on Hawkins Drive in ...

Traffic has slowed on the bridge, at the interchange with Interstate 64 and on southbound I-65 near downtown Louisville, ...

Two Illinois men are in custody at the Lake County Jail following an alleged carjacking on Interstate 65 in Merrillville ...

A Greenville man died Saturday morning when the 18-wheeler he was driving left the interstate and struck several trees, authorities say.

GLENDALE Ky. (WBKO) - The Glendale Fire Department responded to a vehicle accident on Interstate 65 this morning. While crews ...

A man was killed in a crash in south central Kentucky Saturday morning, according to Kentucky State Police. Just before 10 ...

Louisville Metro Police Department says a person was killed in a rollover crash on Interstate 65 Friday evening.

An Illinois man was arrested Monday morning on multiple charges following an investigation that covered three counties along ...