Replacing wide receiver Brandon Aiyuk quickly shot up the San Francisco 49ers’ list of priorities when the 2023 All-Pro went down with a season-ending knee injury in Week 7. Aiyuk’s

Talanoa Hufanga, an All-Pro safety in 2022, has played in just one game after recovering from a torn ACL, was felled by a wrist injury, placed on injured reserve and not eligible to return until Week 11. Linebacker Dre Greenlaw remains on the physically unable to perform list rehabbing an Achilles’ tear and his return date has not been determined.

San Francisco 49ers wide receiver Brandon Aiyuk underwent tests that confirmed he suffered a season-ending knee injury on Sunday.