Choosing the proper sample size for an investigation is one of the crucial jobs required of a statistician. Regardless of whether the statistician is deciding the number of patients to select in a ...

Power analyses and sample size calculations are important parts of many research projects. Often, before data are even collected, it is necessary to calculate and justify the required sample size for ...

Investigator: Right, here is the data set. What is the P value? Statistician: Oh, hello again. Look, I have some concerns about how the endpoint was assessed... Investigator: Fine, I'll add a sentence ...

For a desired power of detecting the association between a disease and several potential risk factors in case-control studies, Yang (1978, Biometrika 65, 635-640) and Halperin (1980, Biometrika 67, ...

Case-control studies are among the most commonly used means of assessing association between exposure and outcome. Sample size determination and the optimal control-to-case ratio are vital to the ...

Implementation of the Time-to-Event Continuous Reassessment Method Design in a Phase I Platform Trial Testing Novel Radiotherapy-Drug Combinations—CONCORDE BayeSize applies the concept of effect size ...

Precedents set in the historic Barr case continue to raise questions over suitable sample-size criteria. The sample size needed to investigate an out-of-specification (OOS) result continues to be a ...

Define statistical power List the potential consequences of doing a study that has low power, and also a study that has too much power. Explain what a type 1 and type ...