San Francisco 49ers quarterback Brock Purdy returns to action and his first completion goes for a 25-yard gain to wide receiver Jauan Jennings against the Arizona Cardinals.

Watch highlights from the Week 11 matchup between the Seattle Seahawks and the Los Angeles Rams during the 2025 NFL season.

The San Francisco 49ers finished their Week 11 contest with a 41-22 win over the Arizona Cardinals at State Farm Stadium.

The Seahawks scored their first touchdown of the game with 2:27 left in the fourth quarter, a 1-yard run by Kenneth Walker. That made it a one-score game and Seattle has all three timeouts, so the Rams offense will need to put this one away.

In a battle of 7-2 teams, it was the Rams who survived a heavyweight showdown in the NFC West. The Seahawks have no one to blame but themselves, as Sam Darnold threw four interceptions in the loss. Los Angeles now has the inside track to win the division, but these teams will go head-to-head again in Week 16 on "Thursday Night Football."

Seahawks head coach Mike Macdonald discussed the team's narrow loss to the Rams. Despite the defeat, Macdonald praised his team's fighting spirit (0:11). He acknowledged the need to capitalize on scoring opportunities and protect the ball better (0:35).

Check out the San Francisco 49ers biggest moments and game-changing plays from their Week 11 win over the Arizona Cardinals.

Arizona Cardinals vs San Francisco 49ers picks, predictions, odds, win probabilities for NFL Week 11 Sunday game on Nov. 16. Who will win game today?

According to the latest NFL odds, the Rams are favored by three points, while the over/under for total points scored is 48.5. The Rams are -175 money line favorites (risk $175 to win $100), while the Seahawks are +146 underdogs.