The primordial germ cells (PGCs) of a recently metamorphosed juvenile Synaptula hydriformis occur with somatic cells in the germinal epithelium of the gonad. As part of the epithelium, PGCs rest on a ...

Using a molecular cellular compass, individual cells in complex organisms know which way is up or down, in epithelial cells known as apical-basal polarity. Determining the orientation is essential for ...

Adherens junctions (AJs) and cell polarity complexes are key players in the establishment and maintenance of apical–basal cell polarity. Loss of AJs or basolateral polarity components promotes tumor ...

Recent work has revealed an evolutionarily conserved trio of proteins that regulate cell polarity in epithelial cells, embryonic blastomeres and neural precursors. This common cell-polarity mechanism ...

Epithelial cells, which line the surfaces of blood vessels and organs, possess a feature called apicobasal polarity that enables them to distinguish between their exterior and interior environment by ...

WEST LAFAYETTE, Ind. — Pools of stem cells in the apical meristems of plants are key to continued growth and development. Understanding how these stem cells are maintained and balanced against ...