A new research paper titled "Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span" has been published in Aging. The decrease in the podocytes' lifespan and health span ...

The kidneys are vital organs that sustain life by filtering the blood and producing urine. This filtration process takes place in specialized structures called glomeruli, where podocytes play a ...

Unlike other human stem cells, Induced pluripotent stem cells (iPS cells) can be produced directly from adult cells. Now, researchers have shown that human kidney podocytes produced from iPS cells via ...

New research shows that arachidonic acid released during infection worsens podocyte kidney injury by disrupting PKM2-linked ...

Damage to podocytes - a specialized type of epithelial cell in the kidney - occurs in more than 90 percent of all chronic kidney disease. Now researchers at the Stanford University School of Medicine ...

Human stem cells are of great interest in the fields of regenerative medicine and medical research because they reproduce indefinitely and can differentiate into every other cell type found in the ...

Podocytes demonstrate a strong reliance on insulin to function properly, according to a study published in Cell Metabolism (2010;12:329-340). Mice hosting podocytes with no insulin receptors developed ...

A fasting-mimicking diet may promote renoprotection by reducing proteinuria and improving endothelial function. Cycles of controlled fasting may promote regeneration of podocytes in patients with ...

A new study identifies a ceramide-gated Calhm2 calcium influx pathway, driven by Aebp1, that injures podocytes in diabetic ...

BUFFALO, NY-August 8, 2023 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 14, entitled, “Inhibiting ...