Microtubules are dynamic, tubular polymers composed of αβ-tubulin dimers that form an essential framework within eukaryotic cells. They orchestrate a wide range of cellular functions including ...

A multi-institutional research collaboration has revealed that the microtubule network (*1), which plays a vital role in cell construction and polarization (*2), utilizes the phase separation (*3) ...

Plant growth and development are a genetically predetermined series of events but can change dramatically in response to environmental stimuli, involving perpetual pattern formation and reprogramming ...

Some cells, such as immune cells, are highly mobile—they constantly remodel their shape, migrate toward a wound that needs to ...

Researchers have developed photoresponsive derivatives of the anticancer drug Taxol®, which allow light-based control of cytoskeleton dynamics in neurons. The agents can optically pattern cell ...

Proteins containing disordered domains perform many important cellular functions. My lab currently has two main projects, one to dissect the role of tubulin's C-terminal tail in microtubule structure ...

Actin filaments (F-actin) are key components of sarcomeres, the basic contractile units of skeletal muscle myofibrils. A crucial step during myofibril differentiation is the sequential exchange of ...

Huntington’s disease is a rare genetic disorder and a representative neurodegenerative disease, characterized by loss of ...

Huntington's disease is a rare genetic disorder and a representative neurodegenerative disease, characterized by loss of ...

A KAIST research team has discovered that the Huntington protein originally plays a critical role in forming the neuronal cytoskeleton under normal conditions. The findings were published in the ...