The function of an enzyme, critical to most forms of life, has been revealed. A research team, led by the John Innes Centre found that the enzyme DNA topoisomerase VI (topo VI) performs a critical ...

The enzyme PI3K plays a critical role in cell migration. Scientists have long understood this function. But researchers have recently unveiled that a subunit of this enzyme also has the ability to ...

UPTON, NY—Scientists studying a COVID-19 coronavirus enzyme at temperatures ranging from frosty to human-body warm discovered subtle structural shifts that offer clues about how the enzyme works. The ...

Scientists discovered a key molecular switch to keep neurons healthy by controlling the disassembly and assembly of their ...

Researchers from Tokyo Metropolitan University have developed a new structure determination method using Nuclear Magnetic Resonance (NMR) spectroscopy which shows how different parts of complex ...

University of Delaware biochemist Jeff Mugridge is trying to figure out how so-called mRNA eraser enzymes work in our cells, why those erasers can sometimes misbehave and lead to cancer, and how ...

CAMDEN – Since the advent of the Human Genome Project an explosion of data has sent the science world scrambling. There is a growing demand to fine-tune genomic codes, which list the "ingredients for ...

Researchers from Tokyo Metropolitan University have developed a new structure determination method using nuclear magnetic resonance (NMR) spectroscopy which shows how different parts of complex ...

Ubc13, a ubiquitin-conjugating enzyme (Ubc), requires the presence of a Ubc variant (Uev) for polyubiquitination. Uevs, although resembling Ubc in sequence and structure, lack the active site cysteine ...