DNA replication is a complex process with many moving parts. In baker's yeast, the molecular complex Ctf18-RFC keeps parts of the replication machinery from falling off the DNA strand. Human cells use ...
Undergraduate biology students could be forgiven for thinking that scientists have DNA replication all figured out. After all, textbooks present the models of replication so matter-of-factly that it's ...
New findings suggest the end-replication problem, an old standby of biology textbooks, is twice as intricate as once thought. Half a century ago, scientists Jim Watson and Alexey Olovnikov ...
Failures in DNA replication can lead to cancer, birth defects or other harm Video shows single pieces of double-helix DNA being copied Single-molecule view gives new insights into this process ...
Accurate transmission of the genetic information requires complete duplication of the chromosomal DNA each cell division cycle. However, the idea that replication forks would form at origins of DNA ...
DNA replication licensing is now understood to be the pathway that leads to the assembly of double hexamers of minichromosome maintenance (Mcm2–7) at origin sites. Cell division control protein 45 ...
Marie Touchon, Samuel Nicolay, Benjamin Audit, Edward-Benedict Brodie of Brodie, Yves d'Aubenton-Carafa, Alain Arneodo, Claude Thermes, Philip P. Green Proceedings of the National Academy of Sciences ...
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