DNTH212 is a bifunctional fusion protein targeting plasmacytoid dendritic cell (pDC) BDCA2 to reduce Type 1 interferon production, while simultaneously inhibiting BAFF/APRIL to suppress B cell ...
Interferon lambda concentrations in nasal lining fluid fell in or above the predicted therapeutic range with a nasally ...
New research shows how pseudorabies virus protein VP22 hijacks DDX21 to inhibit cGAS activation, weakening type I interferon ...
Therapeutics entered into an exclusive licensing agreement with Nanjing Leads Biolabs for DNTH212, a first and potentially ...
The 2024 Albert Lasker Award for Basic Medical Research is awarded to Zhijian (James) Chen for his landmark discoveries that explain how DNA stimulates immune responses. DNA is best known as genetic ...
Objective Patients with systemic lupus erythematosus (SLE) commonly develop lupus nephritis (LN), the most frequent severe ...
Somatic monoallelic single nucleotide variants in the genes that encode isocitrate dehydrogenase (IDH) 1 and 2 are found in a large subset of diffusely infiltrating gliomas and subsets of acute ...
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