Hemoglobin disorders such as HbS and HbC affect millions of people worldwide. Countries around the world spend substantial resources each year identifying carriers, often relying on detailed ...

(MEMPHIS, Tenn. – July 03, 2023) Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease (SCD) and beta thalassemia. These two common life-threatening anemias afflict ...

AstraZeneca Plc (NASDAQ:AZN) released data from the Phase 3 ALPHA trial of danicopan as an add-on to the standard of care for paroxysmal nocturnal hemoglobinuria (PNH). The data showed that danicopan ...

In neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Parkinson’s, and Alzheimer’s, healthy brain cells are damaged by aberrant reactive oxygen species (ROS). A potential ...

Durable expression of anti-sickling fetal hemoglobin and reduction in sickle hemoglobin ob ...

Noncancerous blood disorders are conditions that affect blood cells, such as red blood cells, white blood cells, and platelets. Blood disorders may cause symptoms and complications, but most are ...

Sickle cell disease (SCD) is a group of hereditary red blood cell disorders. Sickle cell anemia is a type of SCD that occurs when a person inherits genes containing an atypical form of hemoglobin.

Beta thalassemia minor is a blood disorder that can cause mild anemia, but it often doesn't show symptoms. If both parents carry the trait for beta thalassemia minor, there's a higher risk of having a ...

Adenosine base editing restarted fetal hemoglobin expression in cells from patients with sickle cell disease. Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease ...