Setting NFL records is cool - but winning is much cooler in the eyes of Arizona Cardinals QB Jacoby Brissett. In the process of being routed by the San Francisco 49ers in Week 11, Brissett set an NFL record with 47 pass completions today.

The San Francisco 49ers picked off Arizona's Jacoby Brissett twice, a defensive counter to the QB's NFL record 47 completions. Said Malik Mustapha: "Little dink and dunks."

Expert recap and game analysis of the San Francisco 49ers vs. Arizona Cardinals NFL game from November 16, 2025 on ESPN.

An injured Kyler Murray, a depleted backfield and really, inconsistent football. It didn’t stop today either in their loss to the San Francisco 49ers in Week 11. Let’s take a look at some key stats that led to the Cardinals' seventh loss of the season:

The Arizona Cardinals quarterback, who is filling in for the injured Kyler Murray, completed 47 of his 57 pass attempts, setting a new record for completions in a single game. Drew Bledsoe had 45 completions in 1994, and Jared Goff had the same mark in 2019.

Daryl Johnston and Kevin Kugler broke down the San Francisco 49ers massive win over the Arizona Cardinals in Brock Purdy's return.

The San Francisco 49ers scored on the first official snap of the game and didn't look back, routing the Cardinals in 41-22 fashion. Arizona now drops to 3-7 on the year, and it was perhaps their most frustrating loss thanks to their self-induced wounds.