An incident involving San Francisco 49ers star running back Christian McCaffrey led to a punishment from the NFL this weekend.

The 49ers have had a roller-coaster of a season so far. There have been numerous injuries to key players, including Brock Purdy, Fred Warner, and Nick Bosa, as

The Los Angeles Rams face the San Francisco 49ers in an NFL game on Sunday, Nov. 9, 2025 at Levi’s Stadium in Santa Clara, California.

Will 49ers defensive end Bryce Huff return to game action this Sunday for the team's showdown against the Rams?

The San Francisco 49ers tallied a riveting win over the Los Angeles Rams back in Week 5. No one could've seen that win coming from the depleted 49ers on a short

Preview the Week 10 matchup between the Los Angeles Rams and San Francisco 49ers with predictions, odds, over/under, spread, betting lines and more.

The San Francisco 49ers on Saturday elevated rookie DT Sebastian Valdez and D-lineman Clelin Ferrell to face the Los Angeles Rams on Sunday.

For the sixth consecutive game, the San Francisco 49ers will not have Ricky Pearsall available. Pearsall is still working his way back from a PCL injury he suffered in Week 4 against the Jacksonville Jaguars. Initially, the 49ers made it sound like Pearsall's injury wasn't much of a worry.