At least seven people were killed and several others injured after a UPS plane crashed shortly after takeoff near the Louisville International Airport on Tuesday, officials said.  The number of fatalities is expected to increase,

The Federal Aviation Administration (FAA) and the National Transportation Safety Board (NTSB) will lead the investigation into the incident.

First responders are searching for more victims after at least seven people died and 11 were injured when a UPS plane crashed while taking off from the airport in Louisville, Kentucky.

As the sun set and businesses started to close in Louisville, Kentucky, on Tuesday, the evening calm was suddenly shattered by a giant explosion near the city’s airport.

On Tuesday, a UPS cargo plane barreled out of the sky and slammed into a number of businesses on the ground, causing a massive explosion.

A UPS cargo plane, loaded with fuel and bound for Honolulu, crashed shortly past the runway of Louisville Muhammad Ali International Airport at around 5:15 p.m. Nov. 4, marking the deadliest plane crash in the history of UPS Airlines.