A deadly UPS cargo plane crash at Louisville Muhammad Ali International Airport triggered a temporary airfield shutdown, and could lead to delays.

Multiple agencies are responding to a plane crash at the Louisville Muhammad Ali International Airport (SDF) Tuesday night, according to the Louisville Metro Police Department (LMPD). Injuries have been reported in the crash but no further information on the nature of those injuries or the victims has been immediately provided.

Video shows a massive fireball and smoke after UPS Flight 2976 crashed into a Kentucky Petroleum Recycling building during takeoff at the Louisville airport.

People on the ground were horrified to see a A UPS cargo plane barrel out of the sky and slam into a number of businesses on the ground, causing a massive explosion.