In addition to QB C.J. Stroud and K Ka'imi Fairbairn, Houston will be without OLs Tytus Howard and Ed Ingram and d DB Jalen Pitre.

Houston has a 31-16 lead in the rivalry and is 16-7 at home. The Jaguars won two in a row at NGR Stadium before Houston won 24-20 last year. Since 2017, the last time the Jaguars swept the season series, the Texans are 12-3 vs. Jacksonville.

At 3-5, the Texans are in desperate need of a win if they harbor any hope of remaining in the AFC playoff race beyond Thanksgiving. Houston will face Jacksonville without starting quarterback C.J. Stroud, who entered the league's concussion protocol during last week's three-point loss to the Broncos .

The Jacksonville Jaguars will hit the road again with an opportunity to sweep their division rival, the Houston Texans. Here's our bold predictions.

AFC South rivalry between Houston Texans and Jacksonville Jaguars grows more intense with recent history and playoff implications.

Here's who the experts have winning on Sunday afternoon at NRG Stadium between the Jacksonville Jaguars and Houston Texans.

Davis Mills will start for the Houston Texans against the Jacksonville Jaguars in Week 10, but he is already facing significant obstacles.

See an updated list of injuries, with active and inactive players for the Jacksonville Jaguars vs. Houston Texans NFL Week 10 game.

An ankle injury will keep No. 1 wide receiver Brian Thomas Jr. out of the Jacksonville Jaguars' lineup Sunday for a divisional matchup at the Houston Texans.

The Jaguars have a chance to sweep the Houston Texans this season with a win in Week 10. Some major news just released that'll greatly help their chances.