Meanwhile, President Donald Trump has told a White House event the US is striking Iranian drone and missile systems "every single hour".

Israel struck Iranian Supreme Leader Ayatollah Ali Khamenei’s underground bunker in Tehran, revealing extensive tunnel network beneath Iran's capital.

DUBAI, United Arab Emirates (AP) — Iran launched new strikes against Israel and U.S. military bases in the Middle East as aerial attacks resumed early Thursday after an American submarine sank an Iranian warship and Iran threatened the destruction of military and economic infrastructure across the region.

The four US Army reserve soldiers were killed in a drone strike in Kuwait on Sunday, one day after the US and Israel began the operation.

Airstrikes have targeted organizations responsible for suppressing protests and cracking down on separatists, though analysts are skeptical the strategy will work.

Israel launched huge attacks on Iran and Lebanon overnight; Iran’s deputy foreign minister warns that any country joining in US-Israel attacks will become ‘legitimate targets’

By Parisa Hafezi and Steve Holland DUBAI/WASHINGTON, March 6 (Reuters) - Israel carried out heavy air strikes on Hezbollah-controlled southern suburbs of Beirut and started a "broad-scale" wave of attacks against infrastructure in Tehran on Friday,